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Description

This research is focused on retinal pigment epithelial cells ( which contains the LRP 1 receptor These are a single layer of cuboidal cells located at the back of the eye, which are primarily responsible for lipid homeostasis The RPE cell layer forms the outer blood retina barrier ( which functions as a regulator of the movement of solutes from the choroid to the sub retinal space Under normal conditions these cells are mitotically inactive, however under adverse conditions they will proliferate and migrate into the retina, sub retinal space, and into the vitreous This can result in a few diseases which includes but is not limited to, diabetic retinopathy, age related macular degeneration, diabetic macular edema, and proliferative vitreoretinopathy

Publication Date

2021

City

New Orleans

Keywords

Retinal Pigment, Epithelial Cells, LRP-1 Signaling

Disciplines

Arts and Humanities | Biology | Life Sciences | Microbiology | Public Health

Retinal Pigment Epithelial Cells and LRP 1 Signaling

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