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The most frequently diagnosed cancer for women is breast cancer Around 5 10 of diagnosed breast cancer cases are metastatic and close to 30 of patients with early stage disease will go on to relapse with metastatic disease 1 Hormone receptor positive breast cancer makes up 70 of breast cancer cases The first line treatment for breast cancer is endocrine therapy Endocrine therapy, also known as hormone therapy, adds, blocks, or removes hormones to treat the disease There are two types of endocrine therapy for breast cancer One type is drugs that prevent estrogen and progesterone from being available for breast cancer cells to grow The other type of endocrine therapy is drugs or surgery to keep the ovaries from making hormones There are several different types of treatment options (see Figure 1 While we have made many advances in this area, a significant number of patients develop endocrine resistance, prompting the need for newer therapeutic agents 2

Publication Date

Summer 2020

Publisher

Xavier University of Louisiana

City

New Orleans

Keywords

NOVEL THERAPEUTIC AGENTS, BREAST CANCER

Disciplines

Chemistry

DESIGN AND SYNTHESIS OF NOVEL THERAPEUTIC AGENTS FOR VARIOUS FORMS OF BREAST CANCER

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Chemistry Commons

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