Self-Regulation in Chemical and Bio-Engineering Materials for Intelligent Systems

Funding Source

National Science Foundation, Xinyang Normal University

Grant Number

5G12MD007595, 1700429, 8UL1GM118967


Department of Chemistry

Document Type


Publication Date



Herein, the authors review the self-regulation system secured by well-designed hybrid materials, composites, and complex system. As a broad concept, the self-regulated material/system has been defined in a wide research field and proven to be of great interest for use in a biomedical system, mechanical system, physical system, as the fact of something such as an organisation regulating itself without intervention from external perturbation. Here, they focus on the most recent discoveries of self-regulation phenomenon and progress in utilising the self-regulation design. This paper concludes by examining various practical applications of the remarkable materials and systems including manipulation of the oil/water interface, cell out-layer structure, radical activity, electron energy level, and mechanical structure of nanomaterials. From material science to bioengineering, self-regulation proves to be not only viable, but increasingly useful in many applications. As part of intelligent engineering, self-regulatory materials are expected to be more used as integrated intelligent components.


DOI: 10.1049/trit.2018.0004

  • Funding text #1

    This publication was made possible by funding from the NIMHD-RCMI Grant no. 5G12MD007595, the National Institute

  • Funding text #2

    of Minority Health, Health Disparities, and the NIGMS-BUILD Grant no. 8UL1GM118967, and the National Science Foundation (Grant no. 1700429). This publication was also made possible by the Louisiana Cancer Research Consortium. The contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIMHD. The authors appreciate the support of Nanhu Scholars Program for Young Scholars of Xinyang Normal University and the Science and Technology Development Plan (No. J17KA006) from Shandong Provincial Education Department as well. Z.H., K.L and D.H. are equally contributed to this work.